HCM can take a toll on patient health and well-being^1-4

Despite current treatment, hypertrophic cardiomyopathy (HCM) can negatively impact patients’ physical, psychological and social activities^1-5

Category	Patient activity
Physical	Walking and exercise^1,2,5 Sleep^1,2,5 Activities of daily living (including self-care)^1,2
Psychological	Mood (general)^1,2 Anxiety^2-4 Difficulty adapting or adjusting to exercise recommendations^1,2,4 Worry, extending to depression, about their condition, particularly among patients with a family history of cardiomyopathy and sudden death²
Social	Work: patients reported that their HCM symptoms had an impact on their ability to work^2,5 Relationships with family² Relationships with friends/others² Limited ability to travel, engage in social activities as well as impacted physical relationships – all leading to an impaired quality of life²

Naidu, Srihari S, editor. Hypertrophic Cardiomyopathy. Second ed., Springer International Publishing, 2019.
Zaiser E, et al. Patient experiences with hypertrophic cardiomyopathy: a conceptual model of symptoms and impacts on quality of life. J Patient Rep Outcomes 2020;4(1):102.
Cox S, et al. Health related quality of life and psychological wellbeing in patients with hypertrophic cardiomyopathy. Heart 1997;78(2):182-7.
Luiten RC, et al. Exercise restrictions trigger psychological difficulty in active and athletic adults with hypertrophic cardiomyopathy. Open Heart. 2016;3(2):e000488.
Ommen SR, et al. 2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 2020;142(25):e558-e631.